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Effects of camptothecin, etoposide and Ca2+ on caspase-3 activity and myofibrillar disruption of chicken during postmortem ageing
Caspase-3 Ageing Ca2+ Camptothecin Etoposide Apoptosis
2012/8/14
Recently, a novel consideration has focused on the potential relationship of apoptosis and the protease caspases and the underlying mechanism for meat postmortem tenderization. In this study, apoptosi...
Affinity of new anticancer agent, 7-trimethylsilyl-ethyl-10-amino-camptothecin, to membranes and HSA determined by fluorescence spectroscopy methods
camptothecin silatecan fluorescence anisotropy
2011/5/6
The application of fluorescence anisotropy measurements in determining the properties of camptothecin analogue 7-trimethylsilylethyl-10-amino-camptothecin – a promising anticancer agent – is described...
Deactivation rate of camptothecin determined by factor analysis of steady-state fluorescence and absorption spectra
camptothecin fluorescence absorption factor analysis
2011/4/28
Camptothecin is a fluorescent compound exhibiting strong anticancer properties. A serious limitation to clinical application of this compound is its hydrolysis, when biologically active lactone form c...