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MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria bec...
Study shows limitations of method for determining protein structure（图）
Study limitation determine protein structure
2019/10/17
A new study by chemists at the University of Arkansas shows that X-ray crystallography, the standard method for determining the structure of proteins, may provide inaccurate information about a critic...
Genomic structure and expression of the porcine ACTC1 gene
actin, alpha cardiac muscle 1 mRNA pig transcription profiling RT-qPCR
2018/11/23
A partial cDNA (~1200 bp) of the porcine ACTC1 gene was identified in the subtracted foetal hind limb muscle cDNA library (44 days of gestation; using m. biceps femoris cDNA as the driver). Using spec...
Unexpected protein structure findings could lead to new therapies
protein structure lead to new therapies
2017/4/27
Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings, published April 5...
Scientists discover the evolutionary link between protein structure and function
Scientists evolutionary link protein structure function
2016/5/31
Proteins are more than a dietary requirement. This diverse set of molecules powers nearly all of the cellular operations in a living organism. Scientists may know the structure of a protein or its fun...
Genetic Structure Among 50 Species of the Northeastern Pacific Rocky Intertidal Community
Northeastern Pacific Rocky Community
2015/12/11
Comparing many species’ population genetic patterns across the same seascape can identify species with different levels of
structure, and suggest hypotheses about the processes that cause such variat...
Penn Researchers Use Nanoscopic Pores to Investigate Protein Structure
Penn Researchers Nanoscopic Pores Protein Structure
2015/9/9
University of Pennsylvania researchers have made strides toward a new method of gene sequencing a strand of DNA’s bases are read as they are threaded through a nanoscopic hole.In a new study, they hav...
Porcine perilipin (PLIN) gene: Structure, polymorphism and association study in Large White pigs
pig perilipin polymorphism
2015/6/8
Perilipin, encoded by the PLIN gene, is a lipid droplet-associated phosphoprotein that functions as a key regulator of triacylglycerol storage and hydrolysis in adipocytes. In this study, structure an...
Construction of a Database of Secondary Structure Segments and Short Regions of Disorder and Analysis of Their Properties
Database Short Regions
2015/5/27
Prediction of the secondary structure of a protein from its amino acid sequence
remains an important task. Not only did the growth of database holding only
protein sequences outpace that of solved p...
Protein function prediction by integrating sequence, structure and binding affinity information
protein function binding affinity information
2015/5/26
Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to ...
STRUCTURE-FUNCTION ANALYSIS OF CXXC FINGER PROTEIN 1
differentiation CXXC finger protein 1 histone methylation
2015/5/25
This dissertation describes structure-function studies of CXXC finger protein 1 (Cfp1), encoded by the CXXC1 gene, in order to determine the functional significance of Cfp1 protein domains and propert...
The influence of the Ku80 carboxy-terminus on activation of the DNA-dependent protein kinase and DNA repair is dependent on the structure of DNA cofactors
DNA-PK Ku70/80 Ku80 Carboxy Terminus
2015/5/25
In mammalian cells DNA double strand breaks (DSBs) are highly variable with respect to sequence and structure all of which are recognized by the DNA- dependent protein kinase (DNA-PK), a critical comp...
New lab technique simultaneously reveals structure and function of proteins critical in DNA repair
structure and function proteins critical DNA repair
2015/4/29
By combining two highly innovative experimental techniques, scientists at the University of Illinois at Urbana-Champaign have for the first time simultaneously observed the structure and the correlate...
Dispersal at a Snail’s Pace: Historical Processes Affect Contemporary Genetic Structure in the Exploited Wavy Top Snail (Megastraea undosa)
fisheries larval dispersal management
2015/12/11
We used population genetics to assess historical and modern demography of the exploited wavy top snail, Megastraea undosa,
which has a 5–10 day pelagic larval duration. Foot tissue was sampled from ...
Fine-scale genetic structure and dispersal distance in the harvester ant Pogonomyrmex barbatus
dispersal distance Fine-scale genetic structure
2015/12/10
Dispersal has important genetic and evolutionary consequences. It is notoriously difficult to study in some ant
species, because reproductives fly from parent nests to
mating aggregation...