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Background: Low potassium has been identified both as a risk factor for type 2 diabetes and as a mediator of the racial disparity in diabetes risk. Low potassium could be a potentially modifiable risk...
Background: Reduced potassium excretion caused by angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) may increase the risk of hyperkalemia (serum potassium conce...
Background: The intake of sodium, chloride, and potassium is considered important to healthy nutrition and cardiovascular disease risk. Estimating the intake of these electrolytes is difficult and usu...
the KATP channels are inhibited by direct ATP binding to the Kir pore-forming subunit, preventing K+ flux across the membrane ,sarcolemma (sarcKATP) membrane the inner membrane of the mitochondria.
Mitochondria are structurally complex. The inner membrane contains the essential components of the electron transport proteins and all of the exchange carriers.
We measured mitochondrial redox potential as an index of mitoKATP channel opening in rabbit ventricular myocytes. The NO donor S-nitroso-N-acetyl- DL-penicillamine (SNAP, 0.1 to 1 mmol/L) oxidized t...
ptosis contributes to ischemic injury in the brain, 4 and brain mitochondria contain 7 times more mitoK ATP channels than heart mitochondria. 5 Several reports have shown that mitoKATP chann...

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