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Enzymes use protein architecture to impose specific electrostatic fields onto their bound substrates, but the magnitude and catalytic effect of these electric fields have proven difficult to quantify ...
Vibrational Stark effect spectroscopy was used to measure electrostatic fields in the hydrophobic region of the active site of human aldose reductase (hALR2). A new nitrile-containing inhibitor was de...
The thousands of enzyme structures solved to date have consistently revealed that biological catalysis occurs within sequestered pockets containing complex interdigitations of polar and hydrophobic gr...
The electric fields produced in folded proteins influence nearly every aspect of protein function. We present a vibrational spectroscopy technique that measures changes in electric field at a specific...
专著信息 书名 Synthesis, Structures and Electrochemical Properties of Nitro- and Amino-Functionalized Diiron Azadithiolates as Active Site Models of Fe-Only Hydrogenases 语种 英文 撰写或编译 作者 Tianbiao Liu,Mei Wang...
专著信息 书名 Synthesis,structures and electrochemical properties of nitro-and amino-functionalized diron azadithiolates as active site models of Fe-only Hydrogenases, 语种 英文 撰写或编译 作者 T. Liu,M. Wang,Z. Shi,H...

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