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Integrative approaches for microRNA target prediction: combining sequence information and the paired mRNA and miRNA expression profiles
miRNA target prediction expression profile integrative analysis
2016/1/25
Gene regulation is a key factor in gaining a full understanding of molecular biology. microRNA (miRNA), a novel class of non-coding RNA, has recently been found to be one crucial class of post-transac...
从参数训练、参数范围训练、候选成熟体打分等方面改进miRNA预测系统MiRfilter，使其适应拥有更长前体的植物miRNA的预测.预测毛果杨基因组上的miRNA，并对系统进行精度检验.利用MiRfilter系统共预测出3 860条候选miRNA；在110个正样本中，正确识别91条前体和80条成熟体，前体预测精度为82.73%，成熟体预测精度为72.73%；在毛果杨第4号染色体（LG_Ⅳ）上得到的...