搜索结果: 1-15 共查到“理学 Mutations”相关记录23条 . 查询时间(0.078 秒)
Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development. However, for the vast majority of those mutations, researchers are unsure of how they contribute to...
Gene editing, or purposefully changing a gene’s DNA sequence, is a powerful tool for studying how mutations cause disease, and for making changes in an individual’s DNA for therapeutic purposes. A nov...
Portland State research shows some viruses can infect even after major mutations
Portland State research some viruses infect
2017/3/30
Portland State University researchers have found that only about half the genes in a specific virus affecting single cell organisms is needed to infect a host. This means the virus can undergo major m...
Model expands landscape for signaling protein mutations
Model expands landscape signaling protein
2016/11/4
Protein pairs that control stimulus response in bacteria maintain a sensitive balance between interaction specificity and promiscuity, according to Rice University scientists.A computational model dev...
Probing Excited-State Electron Transfer by Resonance Stark Spectroscopy:4.Mutations near BL in Photosynthetic Reaction Centers Perturb Multiple Factors that Affect BL/fBL+HL
Excited-State Electron Transfer Resonance Stark Spectroscopy Mutations near BL Photosynthetic Reaction Centers Perturb Multiple Factors BL/fBL+HL
2016/5/24
Stark spectra have been obtained in the region of absorption by the accessory bacteriochlorophylls (the B-band region around 800 nm) in Rhodobacter sphaeroides reaction centers. The Stark spectra in t...
Missense mutations in exon 2 of the porcine leptin receptor gene and their associations with litter size and body weight
LEPR SNPs pigs
2015/6/8
Leptin receptor (LEPR) gene is regarded as a “candidate-gene” of production traits. The aims of this study were to detect polymorphisms of exon 2 within LEPR gene and to investigate their associations...
Making Mutations: Objects, Practices, Contexts.
Modulation of epidermal growth factor receptor function by mutations within the actin -binding domain
Genes actin internalization growth factors tyrosine phenylalanine glutamic acid phenylalanine residues
2014/12/11
The generation of site-directed mutants within the actin binding domain of the EGF receptor modulates receptor function in internalization and ligand binding. In addition, truncation of the EGFr at re...
Molecular and functional analysis of mutations that result in insecticide resistance in Colorado potato beetle
Gene mutations pain and the potato beetle biological molecules the rate constant
2014/12/11
The functional aspects of specific mutations, R30K, S291G, and I392T, found associated with AChE gene of OP- and carbamate-resistant Colorado potato beetle (CPB) were determined using recombinant AChE...
Classification of gene mutations in a children's cancer may point to improved treatments（图）
gene cancer
2014/12/1
Oncology researchers studying gene mutations in the childhood cancer neuroblastoma are refining their diagnostic tools to predict which patients are more likely to respond to drugs called ALK inhibito...
Fifteen years ago, MIT professor John Essigmann and colleagues from the University of Washington had a novel idea for an HIV drug. They thought if they could induce the virus to mutate uncontrollably,...
Mutations of TYR and MITF Genes are Associated with Plumage Colour Phenotypes in Geese
Goose TYR and MITF Gene SNP Plumage Colour
2016/5/16
The polymorphism of microphthalmia-associated transcription factor (MITF) and tyrosinase (TYR) genes have been proposed to play a vital role in coat colour genesis in mammals, but their role remains a...
Detecting mutations in mixed sample sequencing data using empirical Bayes
Detecting mutations mixed sample sequencing data empirical Bayes
2012/11/23
We develop statistically based methods to detect single nucleotide DNA mutations in next generation sequencing data. Sequencing generates counts of the number of times each base was observed at hundre...
Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations
Soluble oligomerization beneficial fitness effect destabilizing mutations Biomolecules
2012/4/28
Mutations create the genetic diversity on which selective pressures can act, yet also create structural instability in proteins. How, then, is it possible for organisms to ameliorate mutation-induced ...
A branching diffusion model of selection: from the neutral Wright-Fisher case to the one including mutations
Diffusions Doob transform killing, branching quasi-stationarity Wright-Fisher model neutral or with mutation selection
2011/10/8
Abstract: We consider diffusion processes x_{t} on the unit interval. Doob-transformation techniques consist of a selection of x_{t}-paths procedure. The law of the transformed process is the one of a...