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高脂日粮模式已广泛应用于鱼类养殖中，但同时也引发了肝脏脂肪过度沉积等问题。二十二碳六烯酸（Docosahexaenoic acid，DHA, 22:6n-3）对鱼类生理及发育具有重要意义。近期，中国农业科学院饲料研究所水产微生物与饲料团队评估了DHA添加比例对鱼类肝脏脂肪的蓄积效应，揭示了作用机制。相关研究成果发表在《Frontiers in Nutrition》
研究发现，在鱼类高脂日...
为建立富含二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)型结构磷脂的制备方法,本试验以南极磷虾磷脂为原料,以EPA和DHA总结合率为指标,通过响应面法优化富含EPA/DHA型结构磷脂的酶法合成反应参数,并采用气相色谱(GC)和亲水作用色谱-质谱联用(HILIC-MS)技术对其结构进行表征。结果表明,最优酶催化反应条件为:底物质量比(游离脂肪酸:磷脂, m/m)5.15,反应温度55.22℃,水分...
观察DHA对七氟烷诱导的小胶质细胞TLR4/MyD88/NFκB信号通路激活及炎症介质释放的影响。方法： N9小鼠小胶质细胞分为Con组、Sevo组和DHA+Sevo组，药物处理各组细胞24h后，采用MTT方法检测小胶质细胞存活率，采用western blot方法检测小胶质细胞TLR4、MyD88和IκB-α的表达量，检测各组培养基中炎症介质TNF-α、IL-1β和IL-6的含量。
Eggs early in complementary feeding increase choline pathway biomarkers and DHA: a randomized controlled trial in Ecuador
egg nutrition children choline betaine vitamin B-12 docosahexaenoic acid
2018/11/21
Background: Choline status has been associated with stunting among young children. Findings from this study showed that an egg intervention improved linear growth by a length-for-age z score of 0.63.
DHA-rich n–3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
fish oil DHA EPA DNA methylation LINE-1 Alzheimer disease
2018/11/20
Background: Dietary fish oils, rich in long-chain n–3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n–3) and eicosapentaenoic acid (EPA, 20:5n–3)], modulate inflammatory reactions thro...
Prenatal supplementation with DHA improves attention at 5 y of age: a randomized controlled trial
attention child development fatty acids prenatal supplementation omega-3 fatty acids preschool cognitive development
2018/12/14
Background: Docosahexanoic acid (DHA) is an important constituent of the brain. Evidence from well-designed intervention trials of the long-term benefits of increasing DHA intake during pregnancy has ...
Prenatal supplementation with DHA improves attention at 5 y of age: a randomized controlled trial
attention child development fatty acids prenatal supplementation omega-3 fatty acids preschool cognitive development
2018/12/18
Background: Docosahexanoic acid (DHA) is an important constituent of the brain. Evidence from well-designed intervention trials of the long-term benefits of increasing DHA intake during pregnancy has ...
A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study
DHA EPA inflammation men and women randomized controlled trial risk factors
2018/12/13
Background: To date, most studies on the anti-inflammatory effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in humans have used a mixture of the 2 fatty acids in various forms and...
DHA supplementation during pregnancy does not reduce BMI or body fat mass in children: follow-up of the DHA to Optimize Mother Infant Outcome randomized controlled trial
body composition growth maternal nutrition omega-3 pregnancy
2018/11/30
Background: The omega-3 (n–3) long-chain polyunsaturated fatty acid (LCPUFA) docosahexaenoic acid (DHA) has proven effective at reducing fat storage in animal studies. However, a systematic review of ...
Maternal single nucleotide polymorphisms in the fatty acid desaturase 1 and 2 coding regions modify the impact of prenatal supplementation with DHA on birth weight
birth weight DHA FADS long-chain PUFAs prenatal supplementation
2018/11/29
Background: Specific single nucleotide polymorphisms (SNPs) in the fatty acid desaturase (FADS) gene affect the activity and efficiency of enzymes that are responsible for the conversion of polyunsatu...
投加FeSO4对序批式生物膜反应器中DHA、EPS和处理效果的影响
硫酸亚铁 化学协同除磷 脱氢酶活性 胞外聚合物
2016/8/15
针对化学协同生物除磷过程，研究了序批式生物膜反应器（SBBR）中FeSO4对悬浮相活性污泥脱氢酶活性（DHA）、胞外聚合物（EPS）及系统处理效果的影响.结果表明，少量FeSO4对DHA和EPS的分泌具有促进作用，但最佳投加量不一致，分别为0.10 mmol·L-1和0.20 mmol·L-1；大量的FeSO4则会引发抑制.FeSO4投加量少于0.30 mmol·L-1时会使污泥MLVSS、MLV...
Long-term effect of high-dose supplementation with DHA on visual function at school age in children born at <33 wk gestational age: results from a follow-up of a randomized controlled trial
docosahexaenoic acid DHA preterm infant very preterm visual processing
2018/11/26
Background: Children born preterm are at risk of visual-processing impairments. Several lines of evidence have contributed to the rationale that docosahexaenoic acid (DHA) supplementation of preterm i...
DHA- Rich Fish Oil Improves Complex Reaction Time in Female Elite Soccer Players
Fatty acids omega 3 efficiency decision-making
2015/5/7
Omega-3 fatty acids (n-3) has shown to improve neuromotor function. This study examined the effects of docosahexaenoic acid (DHA) on complex reaction time, precision and efficiency, in female elite so...
为研究EPA和DHA对黄鳝脂类代谢、生长及繁殖性能的影响, 用添加有EPA和DHA比例相同(EPA/DHA=0.35)但水平不同(EPA和DHA总量分别为0.00%、0.35%、0.70%)的3种等氮等脂肪饲料,在常温(22—30 ℃)下,分别喂养平均体重为(21.71±0.54)g的黄鳝7周,分析黄鳝脂类代谢和生长性能,然后每组取15尾继续养殖至性腺发育成熟用于繁殖性能分析。结果表明:在饲料中添...
对缩减轮数DHA-256的原像与伪碰撞攻击
DHA-256散列函数 原像攻击 伪碰撞攻击 中间相遇攻击
2014/3/21
提出了对DHA-256散列函数37轮的原像攻击以及39轮的伪碰撞攻击。基于中间相遇攻击，利用Biclique方法可以改进之前对DHA-256的原像分析结果，将攻击轮数从原来的35轮提高到了37轮。通过上述方法还可以构造对DHA-256的39轮伪碰撞。最终，以2255.5的时间复杂度以及23的空间复杂度构造了对DHA-256的37轮原像，并以2127.5的时间复杂度以及常数2的空间复杂度构造了对DH...