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Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
Comparative Cytotoxicity of Fludarabine in Human Peripheral Blood Mononuclear Cells and in the Promyelocytic Leukemia Cell Line (HL60)
HL60 MTT assay fludarabine cytotoxicity differentiation
2009/6/23
Fludarabine is an inhibitor of DNA/RNA synthesis with antitumor activity on lymphoproliferative malignancies. We investigated the dose-dependent cytotoxic effects of the drug on human peripheral blood...
The Effect of Suplatast Tosilate on TARC Production in Peripheral Blood Mononuclear Cells and TARC Plasma Levels
allergic rhinitis chemokines suplatast tosilate TARC
2010/11/22
Suplatast tosilate significantly reduced TARC production by PBMCs. TARC mRNA was also suppressed in a concentration dependent manner. However, suplatast tosilate did not inhibit the expression of CCR-...
Bronchial and nasal responsiveness in atopic asthma and allergic rhinitis patients: Relationship of local responsiveness to cytokine production by peripheral blood mononuclear cells
allergic rhinitis atopy bronchial asthma bronchial responsiveness interleukin-4 interleukin-5 nasal responsiveness
2010/11/29
To investigate the relationship between local responsiveness and allergic symptoms, bronchial and nasal responsiveness were measured in the following four groups of subjects: (i) bronchial asthma pati...