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2017 I型干扰素 Keystone Symposia（2017 Keystone Symposia on Type I Interferon: Friend and Foe Alike）
Immune Signal Nucleic Acids
2017/1/13
The meeting will begin on Sunday, March 19 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, March 23 with a closing plenary sessio...
Interferon-Beta-1b Induced Autoimmune Hemolytic Anemia in a Patient with MS: A Case Report
Multiple sclerosis Interferon beta Haemolytic anemia
2015/9/22
A 26-year old lady with the diagnosis of multiple sclerosis who had received interferon beta1-b for eleven months was visited in MS clinic of our hospital because of icter and fatigue. Laboratory test...
Exposure to increased pressure or hyperbaric oxygen suppresses interferon-gamma secretion in whole blood cultures of healthy humans
Analysis of Variance Atmospheric Pressure CD4-Positive T-Lymphocytes Double-Blind Method Hematocrit
2009/6/5
This study examines the effects of hyperoxia, increased atmospheric pressure, and hyperbaric oxygen on cytokine synthesis. Five healthy volunteers were exposed to 90 min of room air, 100% oxygen, 10.5...
Sterile Corneal Ulcer and Sjögren’s Syndrome Associated with Long-Term Interferon alpha-2b Treatment in a Case of Multiple Myeloma
corneal ulcer interferon alpha-2b dry eyes Sjö gren’s syndrome immunosuppressant
2009/4/20
A 71-year-old Chinese male was referred for severe dry eyes who suffered from multiple corneal melting ulcers and underwent a long-term and high-dosage interferon alpha-2b (INFα-2b) treatment for mult...
Interferon-gamma liniment protects hairless mice against ultraviolet irradiation-induced skin damage
Interferon-gamma liniment protects hairless mice ultraviolet irradiation-induced skin damage
2009/3/3
Ultraviolet B (UVB) irradiation has been reported as one of causes of epidermal carcinoma and also one of immunosuppressive inducers associated with an up-regulated production of T helper (Th) 2-typ...
Inhibition of chlamydia trachomatis growth by human interferon-α：mechanisms and synergistic effect with interferon-γ and tumor necrosis factor-α
chlamydia trachomatis growth human interferon-α synergistic effect interferon-γ and tumor necrosis factor-α
2009/3/3
We have evaluated the effect of natural human interferon (IFN)-α on the growth of chlamydia trachomatis in human epithelial cells in vitro and revealed that IFN-α has reduced both growth and infecti...
Repeated regression of pulmonary metastases from renal cell carcinoma after treatment using different interferon-alpha preparations
pulmonary metastases renal cell carcinoma interferon-alpha preparations
2009/3/2
A 49-year-old man with pulmonary metastasis from renal cell carcinoma (RCC) was treated with recombinant IFN-α2b (Intron A®). A complete response was achieved within 4 months and thereafter pers...
Antitumor effects of a combination of interferon-alpha and sorafenib on human renal carcinoma cell lines
interferon-alpha sorafenib human renal carcinoma cell lines
2009/3/2
To support the role of interferon (IFN)-α and sorafenib combination therapy against renal cell carcinoma (RCC), the effects of IFN-α and sorafenib on tumor growth, vascular endothelial growth factor...
A pilot study demonstrating clinical benefit from intralesional interferon alpha 2B in the treatment of Peyronie's disease
Nonsurgical therapy intralesional IFN-a-2B
2009/2/18
Intralesional therapy is a less invasive method for the treatment of Peyronie's disease. The objective of this study was to evaluate intralesional injections of interferon alpha 2B (IFN-alpha-2B) ...
Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells
murine interleukin-2 gamma interferon tumor necrosis factor testosterone synthesis
2009/2/11
It was recently observed that treatment of patients with a high dosage of human interleukin (IL-2) resulted in suppression of plasma concentrations of testosterone. A murine model was developed to a...
The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro
Tumor necrosis factor interleukin-1 interferon human sperm motility
2009/2/10
Whether cytokines present in human peritoneal fluid reduce sperm motility, and thus contribute to infertility, is investigated. The human recombinant cytokines, tumor necrosis factor-alpha, interl...
Effects of Interferon-Gamma on Bone Remodeling during Experimental Tooth Movement
Interferon-gamma Rat Local administration Tooth movement Bone remodeling
2008/11/3
Objective: To determine the effects of interferon-gamma (IFN-γ) on bone remodeling during orthodontic tooth movement.Materials and Methods: Thirty adult male Sprague Dawley rats were randomly categori...
IN VITRO SEMI-QUANTITATIVE DETERMINATAION OF HUMAN GAMMA-INTERFERON EXPRESSION BY RT-PCR
semi-quantitative IFN-γ PHA
2010/4/12
Secreted cytokines of Th1 (T-helper)/Th2 cells play an important role in the pathogenesis of many diseases. Th1 cells secrete predominantly IFN-γ and IL-2 which regulate cell-mediated immunity against...
Development of Fluorescence-linked Immunosorbent Assay for High Throughput Screening of Interferon-γ
enzyme-linked immunosorbent assay fluorescence-linked immunosorbent assay fluorometric microvolume assay technology high-throughput screening interferon-gamma
2010/11/18
We developed a new system for measuring hIFN-γ using Allophycocyanine (APC) fluorescent protein and compared it with the previous method using Cy5.5. The proposed FLISA had a smaller coefficient of va...
Effect of interferon-α on pulmonary function and airway responsiveness in patients with chronic hepatitis C
airway responsiveness carbon monoxide diffusing capacity chronic hepatitis C interferon-α methacholine pulmonary function
2010/11/25
No patient developed interstitial pneumonia, although there was a tendency for the hemoglobin-adjusted DLCO to decrease. Other pulmonary function test parameters were not affected. Overall, there was ...