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Regulation of mTORC1 by growth factors,energy status,amino acids and mechanical stimuli at a g lance
mTORC1 Akt Myostatin Muscle protein synthesis
2016/5/16
The mechanistic/mammalian target of rapamycin c omplex 1 (mTORC1) plays a pivotal r ole in the regulation of skeletal muscle protein synthesis. A ctivation of the c omplex leads to phosphorylation of ...
Reported evidence suggested that high abundance of intrinsic disorder in eukaryotic genomes in comparison to bacteria and archaea may reflect the greater need for disorder-associated signaling and tra...
Metnase is a novel bifunctional protein that contains a SET domain and a transposase domain. Metnase contains sequence-specific DNA binding activity and sequence non-specific DNA cleavage activity, as...
Identification of a Minimal Cis-element and Cognate Trans-factors Required for the Regulation of Rac2 Gene Expression during K562 Cell Differentiation
Rac2 Gene Expression
2015/5/25
This dissertation examines the molecular mechanisms regulating Rac2 gene expression during cell differentiation and identification of a minimal cis-element required for the induction of Rac2 gene expr...
A review of factors affecting the success of membrane protein crystallization using bicelles
Biochemistry bicelle membrane protein crystallization
2015/1/7
Several reports have been published detailing various platforms for obtaining crystals of membrane proteins to determine their structure including those that use disk shaped bilayers called bicelles. ...
May 11, 2007，Scientists have discovered three unsuspected regions of human DNA that contain clear genetic risk factors for type 2 diabetes, and another that is associated with elevated blood triglycer...
Landmark study highlights complex genetic risk factors behind type 2 diabetes
genetics diabetes
2007/4/27
26 April 2007，A UK collaboration of scientists has identified three new genes that predispose individuals to develop type 2 diabetes, bringing scientists a step closer towards understanding what cause...
Effect of some non-genetic factors on the growth of kids of the brown short-haired breed
goat growth traits kid brown short-haired
2015/6/1
The evaluation of effects of some non-genetic factors (sex, litter size, age of dams and year of study) on the growth of 85 kids of the Brown Short-haired breed was carried out in a period of two succ...