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Two single nucleotide polymorphisms in the caprine GnIH gene are associated with litter size
PCR-RFLP SNPs combined genotype candidate gene
2017/6/22
Gonadotropin-inhibitory hormone (GnIH) can decrease luteinizing hormone and/or follicle-stimulating hormone levels in rat, mouse, sheep, and cattle by the direct suppression of gonadotropin-releasing ...
Association of the Single Nucleotide Polymorphisms in RUNX1, DYRK1A, and KCNJ15 with Blood Related Traits in Pigs
Positional Candidate Gene Blood Related Traits Association Test Landrace Korean Native Pigs
2016/12/28
The aim of this study was to detect positional candidate genes located within the support interval (SI) regions based on the results of red blood cell, mean corpuscular volume (MCV), and mean corpuscu...
Y-Single Nucleotide Polymorphisms Diversity in Chinese Indigenous Horse
Chinese Indigenous Horse Y Chromosome Single Nucleotide Polymorphisms Diversity
2016/5/18
In contrast to high genetic diversity of mitochondrial DNA (mtDNA), equine Y chromosome shows extremely low variability, implying limited patrilines in the domesticated horse. In this study, we applie...
Whole Genome Association Study to Detect Single Nucleotide Polymorphisms for Behavior in Sapsaree Dog (Canis familiaris)
Sapsaree Single Nucleotide Polymorphism Behavior Heritability Genome-wide Association
2016/5/18
The purpose of this study was to characterize genetic architecture of behavior patterns in Sapsaree dogs. The breed population (n = 8,256) has been constructed since 1990 over 12 generations and manag...
Genetic Structure of and Evidence for Admixture between Western and Korean Native Pig Breeds Revealed by Single Nucleotide Polymorphisms
Admixture Genetic Diversity Korean Native Pig Single Nucleotide Polymorphism
2016/5/17
Comprehensive information on genetic diversity and introgression is desirable for the design of rational breed improvement and conservation programs. Despite the concerns regarding the genetic introgr...
Identification of Single Nucleotide Polymorphisms (SNPs) of the Bovine Growth Hormone (bGH) Gene Associated with Growth and Carcass Traits in Hanwoo
Bovine Growth Hormone Gene Growth and Carcass Traits Hanwoo, SNP
2016/5/12
The purpose of this study was to find any association of the bovine growth hormone (bGH) gene with growth and carcass quality traits in Korean native cattle, Hanwoo. Genomic DNA was extracted from 21 ...
Single Nucleotide Polymorphisms of NLRP12 Gene and Association with Non-specific Digestive Disorder in Rabbit
NLRP12 SNP Non-specific Digestive Disorder Case-control Study Rabbit
2016/5/12
The NLRP12 (NLR family, pyrin domain containing 12) serves as a suppressor factor in the inflammatory response and protects the host against inflammation-induced damage. In the present study, we aimed...
A Whole Genome Association Study to Detect Single Nucleotide Polymorphisms for Blood Components (Immunity) in a Cross between Korean Native Pig and Yorkshire
WGA SNP Immunity Korean Native Pig Yorkshire
2016/5/11
The purpose of this study was to detect significant SNPs for blood components that were related to immunity using high single nucleotide polymorphism (SNP) density panels in a Korean native pig (KNP)×...
Effect of Single Nucleotide Polymorphisms of Acetyl-CoA Carboxylase α (ACACA) Gene on Carcass Traits in Hanwoo (Korean Cattle)
Acetyl-CoA Carboxylase Gene SNP Marker Carcass Traits Hanwoo
2016/5/6
Meat production and quality traits in beef cattle are largely affected by genetic factors. Acetyl-Coenzyme A carboxylase- (ACACA) plays a key role in the regulation and metabolism of fatty aci...
A Whole Genome Association Study to Detect Single Nucleotide Polymorphisms for Body Conformation Traits in a Hanwoo Population
Whole Genome Association Body Conformation SNP Hanwoo QTL
2016/5/6
A whole genome association (WGA) study was conducted to identify quantitative trait loci (QTL) for body conformation traits in Hanwoo cattle. The phenotypes of 497 steers were recorded from the Hanwoo...
A Whole Genome Association Study to Detect Single Nucleotide Polymorphisms for Carcass Traits in Hanwoo Populations
Single Nucleotide Polymorphism Whole Genome Association Carcass Traits Hanwoo
2016/5/4
The purpose of this study was to detect significant SNPs for carcass quality traits using DNA chips of high SNP density in Hanwoo populations. Carcass data of two hundred and eighty nine steers sired ...
Multifactor Dimensionality Reduction (MDR) Analysis to Detect Single Nucleotide Polymorphisms Associated with a Carcass Trait in a Hanwoo Population
Multifactor-dimensionality Reduction (MDR) SNP Hanwoo Association Study
2016/4/27
Studies to detect genes responsible for economic traits in farm animals have been performed using parametric linear models. A non-parametric, model-free approach using the ??expanded multifactor-dimen...
Associations of Single Nucleotide Polymorphisms in BMPR-IB Gene with Egg Production in a Synthetic Broiler Line
Chicken BMPR-IB Gene SNP Egg Production
2016/4/27
Egg production traits are economically important both for egg-laying and broiler lines of chicken. In sheep, the Q249R mutation in BMPR-IB is associated with ovulation rate. The present study cloned a...
摘要
单核苷酸多态性(SNP)作为第三代遗传标记已经广泛用于基因作图、疾病相关性分析、群体遗传学及药物研究等领域。 文中系统地介绍了目前国内外主要的SNP检测技术，任何一种SNP的检测方法都可将之看成由两部分组成，即区分SNP位点的原理方法和数据的检测分析手段，文章对这两部分做了较详细的介绍，并对SNP检测技术的发展进行了展望。
Abstract :As the third generatio...
摘要
单核苷酸多态性（single nucleotide polymorphism，SNP）是第三代遗传标记，在基因定位、遗传疾病和人类起源等理论研究中具有重大意义, 在抗药性或药物过敏反应中扮演着极其重要的角色，正逐步成为分子诊断、临床检验、新药研发的重要手段。随着人类基因组测序的完成，SNP分型和发现成为遗传和生命医学领域研究的热点之一。近年来，SNP的检测方法层出不穷，发展很快。文章综述和...