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Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells
apoptosis endocycling cells p53 protein
2015/1/7
Apoptotic cell death is an important response to genotoxic stress that prevents oncogenesis. It is known that tissues can differ in their apoptotic response, but molecular mechanisms are little unders...
Correlation of HER2/neu Over Expression,p53 Protein Accumulation and Steroid Receptor Status with Tumor Characteristics: An Iranian Study of Breast Cancer Patients
Breast Cancer HER2/neu p53 Steroid Receptor Stage Iran
2009/12/7
Background: Molecular biomarkers are valuable in evaluation the course of malignancies. In this study, the relationship between HER2/neu, p53, steroid receptors and clinicopathological features o...
Immunohistochemistry Assessment of P53 Protein in Basal Cell Carcinoma
Basal cell carcinoma Gene expression Immunohistochemistry Tumor Suppressor Protein p53
2010/2/3
The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or else induce ...
OVEREXPRESSION OF P53 PROTEIN IN MALIGNANT BREAST TUMORS: AN IMMUNOHISTOCHEMICAL STUDY
overexpressoin cycle regulation
2010/5/7
The P53 protein is expressed in all normal cells and appears to function in cell cycle regulation. Abnormally higli levels of the protein are found in many different types of cancer. In breast cancer,...