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Incorporation of gossypol and formation of its protein conjugates in mouse transformed Sertoli（TM4）cells
protein conjugates mouse transformed Sertoli（TM4）cells
2009/2/23
Mitochondria of both mouse transformed Sertoli (TM4) cells and primary-cultured rat and mouse Sertoli cells were shown to be preferentially affected by gossypol (Tanphaichitr et al, 1984). To invest...
Genetically defined mouse models of male infertility
Genetically defined mouse models male infertility
2009/2/23
The review has four objectives. The first objective is to summarize our studies of gene mutations that induce infertility in male mice. The second objective is to stress the power of mouse genetics ...
Chronic ethanol ingestion during puberty alters the transient increase in testicular 5 alpha-reductase in the Swiss-Webster mouse
transient increase testicular 5 alpha-reductase Swiss-Webster mouse
2009/2/23
Previous experiments with inbred mice showed that chronic ethanol treatment delays male pubertal development. An initial event in sexual maturation in the rat is a transient increase in 5 alpha-re...
Identification and isolation of epididymal luminal proteins of the mouse
Identification isolation epididymal luminal proteins mouse
2009/2/23
Proteins of mouse cauda epididymal fluid were analyzed by polyacrylamide gel electrophoresis. Fluid expressed from the cauda epididymidis and samples obtained by micropuncture of the epididymal lume...
Effects of AMSA, an antineoplastic agent, on spermatogenesis in the mouse
AMSA antineoplastic agent spermatogenesis mouse
2009/2/23
The stages of spermatogenic cells killed by the single and fractionated administration of AMSA, an acridine derivative used in cancer chemotherapy, have been identified in the mouse. A wide range of...
Linear and nonlinear mouse sperm motility patterns
Linear nonlinear mouse sperm motility patterns
2009/2/20
A quantitative method is described for distinguishing two types of mouse sperm motility using a new parameter, the Linear Index. One hundred spermatozoa from C57BL/6-+/+ and 100 spermatozoa from C57...
The effect of testicular x-irradiation on spermatogenesis in man. A comparison with the mouse
irradiation spermatogenesis testicular
2009/2/20
Existing data concerning the effects of x-irradiation on spermatogenesis in man were analyzed and the results were compared to published data on the mouse. Testicular x-irradiation produced a transi...
Effect of Fatty Acids on Fertilization and Development of Mouse Embryos In Vitro
fertilization embryos fatty acids bovine serum albumin
2009/2/19
The interaction of protein and fatty acids on the fertilization and preimplantation development of mouse embryos in vitro was investigated. Normal fraction V and fatty-acid-free bovine serum albumin...
Ca2+ Is Required for Mouse Sperm Capacitation and Fertilization In Vitro
capacitation acrosome reaction whiplash motility A23187 fertilization in vitro calcium
2009/2/19
The temporal involvement of Ca2+ during mouse sperm capacitation in vitro was examined by releasing sperm into Ca2+-free medium and then introducing Ca2+ (1.80 mM, final concentration) at 30 minute ...
Fertilization of Mouse Eggs In Vitro
in vitro fertilization penetration of zona pellucida 3-quinuclidinyl benzilate acrosome reaction sperm binding to zonae mouse sperm mouse eggs inhibition of zona binding
2009/2/19
3-Quinuclidinyl benzilate (QNB) is a potent inhibitor of fertilization of mouse eggs in vitro: it acts by blocking penetration of the zonae by sperm. The time course of this inhibition was examine...
Catecholamine Stimulation of Androgen Production by Mouse Interstitial Cells in Primary Culture
catecholamines Leydig cells androgens cell culture
2009/2/19
The catecholamines isoproterenol, epinephrine, and norepinephrine stimulated androgen production by mouse interstitial cells in primary culture. The amount of androgen produced in response to maximu...
Characterization of Cholinomimetic Agents that Inhibit In Vitro Fertilization in the Mouse
sperm binding cholinomimetics
2009/2/19
Spermatozoa from the cauda epididymidis of the mouse bind 3-quinuclidinyl benzilate (QNB), a highly specific antagonist of the muscarinic type of acetylcholine receptor; inhibition of in vitro ferti...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Construction and preliminary characterization of a series of mouse and rat testis cDNA libraries
Spermatogenesis Sertoli cells peritubular cells gene
2009/2/18
We have constructed a series of 23 cDNA libraries from mouse and rat testicular cells. These include libraries made from whole, intact adult testes; seminiferous tubule cells from adult testes; co...