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Rac Activation Induces NADPH Oxidase Activity in Transgenic COSphox Cells and Level of Superoxide Production is Exchange Factor-Dependent
NADPH oxidase Rac
2014/12/12
Transient expression of constitutively active Rac1 derivatives, (G12V) or (Q61L), was sufficient to induce phagocyte NADPH oxidase activity in a COS-7 cell model in which human cDNAs for essential oxi...
Cloning, Expression, Characterization, and Computational Approach for Cross-Reactivity Prediction of Manganese Superoxide Dismutase Allergen from Pistachio Nut
cloning cross-reaction Manganese Superoxide Dismutase (MnSOD) pistachio (Pistacia vera)
2010/11/12
The MnSOD gene from pistachio was successfully cloned and expressed in E. coli. The purified pistachio MnSOD was recognized by IgE in 10 (40%) out of the 25 sera tested. Our results also showed that t...
Blood Superoxide Dismutase and Catalase Activities in Women Affected with Breast Cancer
Catalase ROS
2009/12/30
Experimental and epidemiological evidences implicate the involvement of oxygen derived radicals in the pathogenesis of cancer development. Oxygen derived radicals are able to cause damage to membranes...
THE PLASMA ANTIOXIDANT ACTIVITY OF SUPEROXIDE DISMUTASE ENZYME IN OSTEOPOROSIS
Osteoporosis SUPEROXIDE DISMUTASE ENZYME PLASMA ANTIOXIDANT ACTIVITY
2009/12/11
Osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. Some studies show that osteoblasts can create inter-cellular free radicals ...
THE PLASMA ANTIOXIDANT ACTIVITY OF SUPEROXIDE DISMUTASE ENZYME IN OSTEOPOROSIS
Osteoporosis SUPEROXIDE DISMUTASE ENZYME PLASMA ANTIOXIDANT ACTIVITY
2009/12/11
Osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. Some studies show that osteoblasts can create inter-cellular free radicals ...
Failure of heparin, superoxide dismutase, and catalase to protect against decompression sickness
Catron,PW Thomas,LB McDermott,JJ Holt,MA Harabin,AL Flynn,ET
2009/7/14
The effects of heparin (HEP), superoxide dismutase (SOD), and catalase (CAT) on the course of decompression sickness (DCS) were studied in anesthetized dogs (Canis familiaris). Animals were divided in...
Age-Related Alterations in Superoxide Dismutase and Catalase Activities in Rat Brain
Aging SOD catalase cerebral cortex cerebellum brain rats
2009/7/2
Active oxygen species have been proposed to be involved in the aging process of the brain, therefore alterations in the activities of enzymes involved in the defense system against free radicals and o...
A Comparison of Erythrocyte Superoxide Dismutase and Catalase Activity in Patients With Hepatitis C Infection
Hepatitis C superoxide dismutase catalase interferon alpha
2009/6/26
Hepatitis C virus (HCV) infection remains important due to difficulties in treatment up to a chronic state. It is considered that free radicals, lipid peroxidation and antioxidant defense play a role ...
Superoxide dismutase responds to hyperoxia in rat hippocampus
Atmospheric Pressure Hippocampus enzymology Hyperbaric Oxygenation animal rat
2009/6/4
The brain's anti-oxidant response to highly elevated oxygen (O2) partial pressures is poorly understood. In this study we hypothesized that hyperbaric O2 (HBO2) would stimulate superoxide dismutase (S...
Morphologic changes induced by short-term ischemia in the rat testis are not affected by treatment with superoxide dismutase and catalase
short-term ischemia rat testis superoxide dismutase and catalase
2009/2/23
Short-term testicular ischemia was induced unilaterally by ligating the testicular artery for 60 or 100 minutes in adult rats. After 7 days, the rats were fixed by vascular perfusion. The effect of ...
Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity
Human spermatozoa liquid peroxidation superoxide production hydrogen peroxide production
2009/2/23
Spontaneous lipid peroxidation in washed human spermatozoa was induced by aerobic incubation at 32 C and measured by malonaldehyde production; loss of motility during the incubation was determined s...
Interaction between Ca2+, cyclic 3',5' adenosine monophosphate, the superoxide anion, and tyrosine phosphorylation pathways in the regulation of human sperm capacitation
Calmodulin phosphatase kinase
2009/2/17
In order to fertilize the egg, spermatozoa must go through the capacitation process where they experience Ca2+ uptake, increases in cyclic 3',5' adenosine monophosphate (cAMP) concentrations, supe...
Human sperm capacitation induced by biological fluids and progesterone, but not by NADH or NADPH, is associated with the production of superoxide anion
Spermatozoa MCLA reactive oxygen species sperm hyperactivation protein tyrosine
2009/2/17
Recent evidence indicated that human sperm capacitation is associated with an increased production of superoxide anion (O2.-). To further study the role and importance of O2.- in capacitation, we in...
Developmental expression of glutathione peroxidase, catalase, and manganese superoxide dismutase mRNAs during spermatogenesis in the mouse
Antioxidant enzymes gene expression testis translational regulation
2009/2/16
We have examined in mouse testis the steady-state levels of mRNAs encoding glutathione peroxidase (GSHPx), catalase (CAT), and superoxide dismutase 2 (SOD-2), three enzymes essential for the antio...
Mechanism of superoxide dismutase loss from human sperm cells during cryopreservation
superoxide dismutase loss human sperm cells cryopreservation
2009/2/12
Earlier studies on human sperm cryodamage have shown that plasma membrane stress is the primary process and that phospholipid peroxidation in cryopreserved samples is not inhibited by addition of an...