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I noticed a technically incorrect definition in an otherwise interesting and potentially important article published recently in the Journal (1). The authors state in the introduction that “Sensitivit...
Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes.
cotranslationally acting chaperones systematic analysis mRNAs associated ribosome-nascent chain complexes
2015/12/11
Polypeptides exiting the ribosome must fold and assemble in the crowded environment of the cell. Chaperones and other protein homeostasis factors interact with newly translated polypeptides to facilit...
Comparison of Detection of Antibodies with Yeast Lysate Antigens Prepared from Two Isolates of Blastomyces dermatitidis by Two Different Methods: Sensitivity and Specificity Evaluations
Isoelectric Focusing ELISA Blastomycosis Lysate Antigen Antibody Detection
2013/1/31
Blastomycosis, a systemic fungal disease, caused by the dimorphic fungus Blastomyces dermatitidis, has continually presented clinicians with concerns with regard to laboratory diagnosis and prevention...
Sensitivity and Specificity Determinations with Isoelectric Focusing Fractions of Blastomyces dermatitidis for Antibody Detection in Serum Specimens from Infected Dogs
Isoelectric Focusing ELISA Blastomycosis Lysate Antigen Antibody Detection
2013/2/19
Blastomycosis and histoplasmosis manifest as lung and systemic fungal infections in mammals caused by Histoplasma capsulatum, and Blastomyces dermatitidis. These infections exhibit cross reactivity of...
A Comparative Study on Sensitivity and Specificity of Conventional and Unconventional IgG and IgM Assays for Diagnosis of Toxoplasmosis
Toxoplasmosis Sensitivity Specificity IgG IgM
2009/12/18
Background: Toxoplasmosis is a zoonotic disease with widespread distribution throughout the world. It is caused by the protozoan parasite Toxoplasma gondii. As laboratory diagnosis of toxoplasmos...
Sensitivity and Specificity of Self-Reported Symptoms for Exercise-Induced Bronchospasm Diagnosis in Children
Exercise-induced bronchospasm Soccer player Spirometry Exercise induced asthma Children
2009/12/14
Objective: Exercise-induced bronchospasm (EIB) is a common condition in elite athletes. The purpose of this study was to evaluate the diagnostic value of self-reported EIB symptoms in children.
Metho...
The Sensitvity,Specificity,Positive and Negative Predictive Values of Stool Color test,Triangular Cord Sign and Hepatobiliary Scintigraphy in Diagnosis of Infantile Biliary Atresia
Biliary atresia Stool color Triangular cord sign Hepatobiliary scintigraphy Liver biopsy
2015/9/18
Background: It is very important to detect biliary atresia in a timely manner to prevent progressive damage to the liver. Our attempt was to formulate our diagnostic approach to infantile cholestasis ...
Estimation of Sensitivity and Specificity for Clustered Data
Sensitivity Specificity Clustered data
2009/6/23
The most commonly used measurements for evaluating the accuracy of diagnostic tests in binary data are sensitivity and specificity. Sensitivity refers to the ability of a test to detect patients with ...
Glycosidic specificity of fucosyltransferases present in rat epididymal spermatozoa
Glycosidic specificity fucosyltransferases present rat epididymal spermatozoa
2009/2/13
We have recently demonstrated multiple fucosyltransferase (FT) activity in rat spermatogenic cells. To complement these findings, here we identify and partially characterize the glycosidic linkage s...
Tissue and species specificity of mouse ductus deferens protein
ductus deferens major protein monoclonal antibodies androgens mouse
2009/2/6
The ductus deferens of the mouse contains a major protein with a molecular weight of 34.5 kd called mouse vas deferens protein (MVDP). Immunofluorescence histochemistry and immunoblotting with monoclo...
Marked species specificity of guinea pig luteinizing hormone：validation of a bioassay
species specificity guinea pig validation of a bioassay
2008/12/26
The Guinea pig is a potentially interesting alternative small animal model for the study of the neuroendocrine regulation of reproduction. However, appropriate gonadotropin assays are not widely ava...
Cell Specificity of Aquaporins 0, 3, and 10 Expressed in the Testis, Efferent Ducts, and Epididymis of Adult Rats
Water transport Sertoli basal nonciliated androgens
2008/12/22
Aquaporins (AQPs) are transmembrane protein channels that allow the rapid passage of water across an epithelium at a low energy requirement, though some also transport glycerol, urea, and solutes ...
PREPARATION OF IMMUNOGEN AND PURIFICA¬TION OF HIGH AFFINITY AND SPECIFICITY FAB FRAGMENT OF ANTI-DIGOXIN POLYCLONAL ANTIBODIES
Anti-Digoxin Polyclonal Antibody High Affinity
2010/4/30
In this study we produced and purified a high titer of specific and high affin¬ity Fab fragments of anti-digoxin antibody. Immunization of rabbits with a conju¬gate of the cardiac glycoside di...