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Risk profiling and surveillance: previous adenomas and colorectal cancer
previous adenomas colorectal cancer
2015/4/13
The brief of this issue of Cancer Forum is to review information available since the 2005 publication of the National Health and Medical Research Council relating to risk management of individuals wit...
Family history of colorectal cancer is a well-established and consistently strong risk factor for this disease. However, simply counting the number of affected relatives is an imprecise measure of col...
The use of gene expression profiling in tumour classification and management
gene expression profiling tumour classification management
2015/3/13
Microarray-based transcript profiling is a technique used to measure the steady-state levels of gene expression on a genome-wide scale in a cell or tissue. The technology essentially involves making a...
MOLECULAR PROFILING IN BREAST CANCER AND TOXICOGENOMICS
molecular profiling,breast cancer toxicogenomics feature selection
2015/1/9
This dissertation presents a body of research that attempts to tackle the ‘overfitting’ problem for gene signature and biomarker development in two different aspects (mechanistically and computational...
Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles
drug development toxicology translational research
2014/11/6
In this study, we compared gene transfer efficiency and host response to ultrasound-assisted, nonviral gene transfer with a conventional plasmid and a minicircle vector in the submandibular salivary g...
Profiling in sport using momentum and perturbations - See more at: http://www.jhse.ua.es/jhse/article/view/545#sthash.ijeofvZ1.dpuf
PROFILING PERFORMANCE SPORT MOMENTUM, PERTURBATIONS
2013/10/1
Examining a team’s performance from a physical point of view their momentum might indicate unexpected turning points in defeat or success. Physicists describe this value as to require some effort to b...
Selecting maximally informative genes to enable temporal expression profiling analysis
Expression profiling regulatory architecture motif discovery
2009/12/24
Use of microarrays to analyze drug responses has mainly been restricted to comparing treated versus untreated samples at a few time points. In order to decipher the complex expression interactions and...
Protein Profiling on Meglumine Antimoniate (Glucantime®) Sensitive and Resistant L. tropica Isolates by 2- Dimentional Gel Electrophoresis: A Preliminary Study
2 Dimentional gel Electrophoresis (2 DE) Protein profiling L.tropica Glucantime Sensitive Iran
2009/12/15
Background: Glucantime® is the first- line drug for the treatment of all forms of leishmaniasis. Unfortunately, the prevalence of parasites becoming resistant to Glucantime® is increasing in s...
High-Speed Fluorescence Imaging and Intensity Profiling of Femtosecond-Induced Calcium Transients
Imaging Calcium Transients
2009/9/8
We have demonstrated a combined imaging system, where the physiology of biological specimens can be imaged and profiled at 10–20 frames per second whilst undergoing femtosecond laser irradiation. Indi...
Tumor mutations can predict chemo success--Genetic profiling of tumors could have 'immediate impact' on treating cancer, study shows
tumor mutations chemo success immediate impact cancer
2009/8/10
New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.The findings should have an imme...
Gene and Protein Profiling of the Response of MA-10 Leydig Tumor Cells to Human Chorionic Gonadotropin
Testis, gene ontology genomics proteomics steroidogenesis
2008/12/22
Activation of the steroidogenic machinery by peptide hormones involves a number of steps for transmitting signals from the plasma membrane to mitochondria in a spatially and temporally coordinated...
Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy
RNA samples autopsy
2006/12/11
4 December 2006，Traditional multiplexed gene expression methods require well preserved, intact RNA. Such specimens are difficult to acquire in clinical practice where formalin fixation is the standard...
In-vivo coronary flow profiling based on biplane angiograms: influence of geometric simplifications on the three-dimensional reconstruction and wall shear stress calculation
In-vivo coronary flow profiling biplane angiograms
2010/2/26
We investigated the influence of two methods of lumen reconstruction, assuming circular versus elliptical cross-sections and using different resolutions for the cross-section reconstructions along the...
Gene Expression Profiling of Human Mast Cell Subtypes: An In Silico Study
carboxypeptidase chymase human mast cells microarray transcriptome
2010/11/18
The MC lineage seems to be far from the granulocyte lineages including basophils. CMA1-high MCs (MCTC) and CMA1-low MCs (MCT) can be regarded as differentiated MC subtypes. As such, importance of data...
《Pharmaceutical Profiling in Drug Discovery for Lead Selection》（图）
Pharmaceutical Profiling in Drug Discovery for Lead Selection Ronald T. Borchardt Edward H. Kerns Christopher A. Lipinski Dhiren R. Thakker Binghe Wang
2013/12/4
Volume 1 of the AAPS Press series, Biotechnology: Pharmaceutical Aspects. Based on a 2003 AAPS workshop of the same name, Pharmaceutical Profiling in Drug Discovery for Lead Selection emphasizes the i...