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目前,食管癌的发病率与死亡率在全球范围内均排在前列,超过一半以上的患者发生在我国,其中约90%的病理类型为食管鳞状细胞癌(esophageal squamous cell carcinoma,ESCC)。通过以往的研究发现,食管鳞癌在基因组变异和肿瘤微环境等方面均具有广泛的肿瘤异质性,而造成食管鳞癌异质性的原因尚不清楚。因此,充分了解肿瘤异质性的特征以及其形成机制将有助于指导食管鳞癌药物开发以及临...
2020年以来,新型冠状病毒肺炎的暴发,在世界范围内给人类生活带来了巨大的影响。我国通过救治病人和严格的非药物干预等措施,迅速控制了疫情在国内的流行;随后,通过对入境人员的全面检测与隔离,有效控制了境外疫情的输入。然而,新冠病毒的感染和传播路径,尚未被完全了解。例如2020年7月以来,我国多地从进口冷冻食品包装表面检测到新冠病毒的核酸,但其传播风险一直不很明确。认真评估食品冷链在病毒感染和传播路径...
Armed with a rapid response research grant from the National Science Foundation, University of Oregon biologist Stilianos Louca and his colleagues are mining public databases for genomi...
Objective. To compare the different philosophies, emphases and processes of national and international accreditation paths available to pharmacy programs in Gulf Cooperation Council (GCC) countries.To...
National Institute of Nursing Research are dedicated to improving the health and health care of Americans through the funding of nursing research and research training. Our mission is to promote and i...
The National Science Foundation (NSF) has agreed to provide a humanitarian medical evacuation flight for an ailing visitor from its Amundsen-Scott South Pole Station to McMurdo Station on the Antarcti...
The National Science Foundation (NSF) has made 11 awards totaling $55 million aimed at building research capacity to address fundamental questions about the brain and develop new innovations at the in...
Few studies describing the growth of adolescents exist because of the difficulties in interpreting anthropometric data in this age group.
Plant sterol esters reduce cholesterol absorption and lower circulating blood cholesterol concentrations when incorporated into the habitual diet.
Serum retinyl ester concentrations are elevated in hypervitaminosis A. It was suggested that retinyl esters > 10% of total serum vitamin A indicate potential hypervitaminosis, but this cutoff was d...
High circulating total homocysteine (tHcy) concentrations are associated with stroke, which is a major cause of cognitive dysfunction. Blood homocysteine concentrations are inversely correlated wit...
Inadequate vitamin A status has been a potential nutritional problem for some segments of the US population, particularly children and the poor.
Nutritive and nonnutritive dietary constituents can promote or hinder the development of several chronic diseases, including cancer, obesity, inflammatory diseases, diabetes, and cardiovascular dis...
Previous studies suggested that diabetes mellitus may lower serum vitamin C concentrations, but most of these studies used clinic-based populations with established diabetes of varying duration and...

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