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Visualizing and predicting evolution by mapping the elusive 'fitness landscape'
Visualizing predicting evolution fitness landscape
2016/4/25
Suppose you were trying to design a vaccine to combat next season's influenza virus. Having a detailed map that tells you exactly how various strains of the flu bug will evolve would be extremely help...
Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations
Soluble oligomerization beneficial fitness effect destabilizing mutations Biomolecules
2012/4/28
Mutations create the genetic diversity on which selective pressures can act, yet also create structural instability in proteins. How, then, is it possible for organisms to ameliorate mutation-induced ...
Speeding up evolutionary search by small fitness fluctuations
Speeding up evolutionary search fitness fluctuations
2011/1/5
We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutuation rate limit, which we model as a biased Langevin process in the genotype space. We show analytically ...
8 February 2007，We may not be as fit as the people of ancient Athens, despite all that modern diet and training can provide, according to research by University of Leeds exercise physiologist, Dr Harr...